natural products from plants can protect the skin against gamma rays at a radiation

natural products from plants can protect the skin against gamma rays at a radiation -

Radiation therapy for cancer involves exposure of the patient or their tumor more directly to ionizing radiation, such as gamma rays or X-rays -of. The radiation damages the cancer cells. Irretrievably Unfortunately, such radiation is harmful to healthy tissue, especially the skin on the site of the tumor, which is then at risk of hair loss, skin problems and even skin cancer. As this finding ways to protect the overlying skin are highly sought after.

Writing in the International Journal of Low Radiation, Faruck Lukmanul Hakkim University of Nizwa, Oman and Nagasaki University, Nagasaki, Japan, and colleagues there and at Macquarie University, New South Wales, Australia, Bharathiar University, India and Konkuk University, South Korea, explain how three natural products ubiquitous and well-studied plant derivatives can protect the skin against gamma rays during the radiotherapy.

Hakkim and colleagues discuss the benefits of, antioxidants, organic acid compounds caffeic (CA), trans-cinnamic acid rosmarinic acid (RA) and (TCA) used for non-toxic concentrations. They tested the protective effect of the radio these compounds against gamma radiation in reducing the levels of reactive oxygen species generated in skin cells by clinically relevant dose of gamma rays in the laboratory and in terms of DNA damage genetic material, in particular double breaks in laboratory samples of human skin cells (keratinocytes). They found that treatment of human skin cells with CA, RA and TCA can protect cells per 40, 20 and 15 percent of the toxicity of gamma rays respectively. They suggest that the protective effect comes from the fact that the compounds absorb the reactive oxygen species and chemically disable and improving mechanisms natural DNA repair of the body.

The team suggests that these compounds could be better used as protective skin during chemo- and radio-therapy combination. Further work is underway to investigate the clinical potential of mixtures of three natural products.