Discovery could lead to new drugs to fight against melanoma -
The cancerous skin cells work together to spread further and faster, according to a new study published in Cell Reports. This discovery could lead to new drugs against melanoma, the deadliest form of skin cancer.
Cancer Research UK scientists at the University of Manchester found that some melanoma cells are particularly fast growing, but not very good to invade surrounding tissue, while others are melanoma cells to opposite -. very invasive but slow growth
In a tumor, piggyback "faster growing cells, as well as more invasive cells, so that together they can be more effective in establishing a new tumor, once they reached different parts of the body.
scientists have conducted research using see-through zebrafish so they could see how moved and expanded cancer cells from the original tumor.
Dr. Claudia Wellbrock, author of the study and Cancer Research UK researcher at the University of Manchester and a member of the Centre for Research on the Manchester Cancer, said: "We used to think that cancer cells spread by first specializing is invading other parts of the body, then change to grow rapidly. But this research shows that melanoma can spread through "cooperative invasion."
" different types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more efficiently. it has profound implications on how we find cures for this terrible disease. "
Melanoma is the most dangerous form of skin cancer, with around 13,300 people diagnosed in the UK each year.
worryingly, malignant melanoma incidence rate increased more than fivefold increased since the mid 1970s
Professor Richard Marais, director of Manchester Institute cancer Research UK, said: "malignant melanoma is the most deadly form of cancer skin, precisely because it spreads rapidly and aggressively. such research is essential to determine how this horrible disease spreads around the body and how we might be able to stop it.
"and to find more effective treatments for advanced melanoma, we must also emphasize the importance of early diagnosis, tumor detection before they have a chance to spread."
EmoticonEmoticon