Study reveals the appearance of the disease for centenarians than younger counterparts delayed -
Research has shown that human life has the potential to be extended. But would this simply means people are living longer in poor health? The optimistic conclusions of a new study in the Journal of the American Geriatrics Society indicate that those extra years may well be healthy ones. In a study of nearly 3,000 people, the onset of the disease came decades later in life for centenarians than their younger counterparts.
"Most people face a burden more and more disease and disability as they age," said study leader Nir Barzilai, MD, professor of medicine and genetics at Albert Einstein College of medicine, Director of the Institute for Aging Research Einstein and attending physician at Montefiore. "But we found exceptionally long life than those living have the added advantage of shorter periods of illness - sometimes weeks or months. - Before the death"
The researchers studied the health status centenarians and centenarians enrolled in almost two ongoing studies: Longevity Genes project (LGP) and the New England centenarian study (NECS). Since 1998, Dr. Barzilai and his colleagues conducted the LGP, which recruits in good health, live independently Ashkenazi Jewish people 95 years and older from the northeastern United States. For comparison, the LGP includes a group of Ashkenazi Jewish individuals who do not have a parental history of longevity. The NECS began in 1994 as a study of all the centenarians living in eight cities near Boston and was later expanded to include participants from North America in general, as well as England, Ireland, Australia and New Zealand. The comparison group consisted of NECS people aged 58 to 95.
This study compared the health of 483 participants in the long term LGP LGP comparison with 696 people aged 60-94 years, and health status of 1498 long-lived participants with 302 NECS NECS comparison aged 58-95 subjects. For both sets of comparisons, the researchers studied the age at which people have developed five main age-related health problems: cancer, cardiovascular disease, hypertension, osteoporosis and stroke. The analysis revealed a consistent pattern of late-onset disease in centenarians groups LGP and NECS compared to their respective comparison groups.
For example, for people in the long term NECS, the cancer has not punished 20 percent of men up to 97 years and women up to 99. However, 20 percent of comparisons NECS participants had developed cancer 67 years for men and 74 for women. The results were similar for LGP for participants LGP long life, the age at which 20 percent had developed cancer was delayed to 96 for both sexes. But the cancer had affected 20 percent of males 78 years of LGP control group and female control group of 74.
Despite their genetic, social and cultural differences, the LGP participants and long NECS life proved to be significantly similar with respect to a serious illness compared to younger control groups, their onset of major disease related to age was delayed, serious illness essentially compressed into a few years late in life . The results suggest that the discoveries in a century-old group can be generalized to diverse populations. And they contradict the idea that people get older, they become sicker and the cost of caring for them.
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