Study identifies genetic as dominant risk factor in breast cancer, prostate and colorectal -
A study of individuals who were adopted identified the genetic as a dominant risk factor in 'family' breast, prostate and colorectal cancer.
researchers from the Centre for Research on Primary Health Care at the University of Lund and Region Sk-do in Sweden presented new research results based on population registers studies.
"the results of our study do not mean that the way of life of an individual is not important to the individual risk of developing cancer, but suggests that the risk for the three types most common cancer depends largely on genetics, "said Bengt Z-ller, a reader at the University of Lund, who led the study.
researchers studied adoptees born in Sweden in connection with both biological parents and adoptive parents. The Swedish Multi-Generation Register and the Cancer Registry were used to monitor 70 965 men and women adopted. They were all born between 1932 and 1969 and developed breast cancer, prostate cancer or colorectal cancer between 1958 and 2010. Using registry studies, the researchers also examined their adoptive parents and biological on same period.
cancer risk among adopted children with at least one biological parent who had the same cancer was 80 percent higher than breast cancer, prostate cancer and colorectal cancer as a control group without a biological parent with the same cancer. There were however a higher risk for people with adoptive parents with breast cancer, prostate cancer and colorectal cancer as a control group. People with a biological parent with cancer has also developed the disease at a younger age than those without a biological parent with the same cancer. The age at which an individual developed cancer, however, was not affected by whether an adoptive parent had the same cancer.
The results are an important indicator of the importance of hereditary factors for breast, prostate and colorectal cancer, according to Bengt-Z ller.
"The occurrence of breast cancer, prostate cancer and colorectal cancer in the biological parents is an important risk factor that should be included in history and medical examinations of patients. There is important that physicians ask questions about family history so they can decide if further tests are needed, "said Bengt-Z ller.
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