Thursday, December 5, 2013

vaccination against HPV can be effective in reducing the results of abnormal Pap tests, even after the first sexual

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vaccination against HPV can be effective in reducing the results of abnormal Pap tests, even after the first sexual -

Minority women who received vaccination against human papillomavirus (HPV), even after becoming sexually active had lower rates of abnormal Pap test than those who have never been vaccinated. These findings appear in the journal Sexually Transmitted Diseases .

School Researchers from Boston University of Public Health and the School of Medicine conducted a cross-sectional study of 235 women age 21 to 30 cytological cervical undergoing routine tests. HPV status and demographic and behavioral characteristics were self-reported and verified with electronic medical records.

"Although the data clearly show better immune response and vaccine efficacy against genital warts and cervical dysplasia when vaccination occurs before 14 years, this study suggests that vaccination against HPV can be effective in reducing the results of abnormal Pap tests, even after the first sexual intercourse, "says co-author Rebecca Perkins, MD, M.Sc., assistant professor of obstetrics and gynecology at the medical faculty of the Boston University and a gynecologist at Boston Medical Center.

at the time of the study, 41 percent had received at least one vaccination against HPV; 97 percent of women were vaccinated after the sexual beginning. Ten percent of the women had abnormal cervical cytology results. The prevalence of abnormal cytology was 65 percent lower among women who received at least one vaccination against HPV compared to unvaccinated women.

The researchers continued monitoring of vaccination against HPV is necessary to identify clinical benefits, especially given the low absorption rate of the vaccine and the completion and immunization a large number of young women after sexual debut. "The studies should continue to compare the efficacy of the vaccine before and after sexual debut and vaccine doses received and to explore the role of herd immunity," said Perkins.


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