Researchers provide overall estimates on the prevalence of HCV genotype -
non-genotype 1 infections account for over 50 percent of all HCV cases
in one of the largest to date of prevalence studies, UK researchers provide national estimates, regional and global prevalence of the genotype of hepatitis C (HCV). The results published in Hepatology, a journal of the American Association for the Study of Liver Diseases, indicate that genotype 1 is the most common worldwide, with more than 83 million infected a third of which reside in Asia from the east. Genotype 3, a little over 54 million cases, is the most common next, followed by genotypes 2, 4, 6 and 5.
Despite efforts against HCV, there remains one of the most widespread diseases in the world, with up to 150 million patients living with chronic infection according to world health Organization (WHO). Previous research shows that chronic HCV leads to cirrhosis development, hepatocellular carcinoma (HCC), or liver cancer, liver failure and death. WHO reports that 350,000 to 500,000 deaths each year are caused by liver disease related to HCV.
"While the rate of HCV infection is decreasing in developed countries, deaths due to HCV liver disease secondary continue increasing over the next 20 years," says lead co Messina-author Dr Jane with Oxford University in the UK "Understanding global trends in the genetic makeup of HCV is the object of our study and imperative to develop new treatment strategies that can save millions of lives around the world. "
researchers identified 1,217 medical studies between 1989 (HCV years was discovered) and 2013 who reported the genotypes of HCV. The data were then combined with estimates of HCV prevalence of wHO on the global burden of disease.. about 0% of the world population, representing 117 countries were included in this study
the analysis showed that genotype 1 HCV is the most prevalent in 46% of all HCV cases, followed by genotype 3 to 30%. genotypes 2, 4 and 6 with a combined total of 23% and genotype 5 to less than 1% the researchers stress that genotypes 1 and 3 are status whatever the most dominant economic, but found the low-income countries had higher concentrations of genotypes 4 and 5.
Dr. Eleanor Barnes with Oxford University adds: . "the trials of new treatments depends not yet aware of the viral genotype HCV genotype 1, comprises more than half of all cases of HCV Our study provides evidence of the prevalence of the genotype for specific countries. areas that will help improve access to new viral therapies to fight against HCV. "
Monday, July 28, 2014, will no-Day World Hepatitis Day was organized by WHO to increase awareness and understanding of viral hepatitis.
EmoticonEmoticon