Partial nephrectomy offers nearly equivalent lengths of fight against cancer compared to radical nephrectomy

Partial nephrectomy offers nearly equivalent lengths of fight against cancer compared to radical nephrectomy -

tumor destruction procedures guided needle offer nearly equivalent lengths of local control cancer compared to surgery for patients with small tumors of kidney cancer, according to results of a large study published in the journal European Urology. "If validated, these data suggest that an update clinical guidelines would be justified," says lead study author, R. Houston Thompson, M.D., a urologist at the Mayo Clinic.

Dr. Thompson said radical nephrectomy - surgical removal of the entire kidney - has always been the standard of care for the management of kidney cancer; However, partial nephrectomy - surgical removal of tumors of a kidney while sparing healthy tissue -Has become more and more common because of its advantages nephron savings and similar fight against cancer. The nephron is the part of the kidney that filter toxins from the blood.

"We undertook this study because direct comparisons of results in patients with kidney cancer who received partial nephrectomy (PN), radiofrequency ablation (RFA) - Destruction of the tumor using intense heat and cryoablation - destruction of the tumor using extreme cold. - lacking, especially institutions that regularly perform all three of these procedures, "says Dr. Thompson

the researchers studied a total of 1,803 patients. among patients with tumors 4 cm or less, 1,057 patients received PN, 180 received RFA and 187 received cryoablation. recurrence-free survival was similar between the three treatment groups while metastasis-free survival was significantly better for patients who received PN and cryoablation compared to patients treated with RFA. for 379 patients with tumors 4-7 cm, length of recurrence-free survival without metastases were Similar between PN and cryoablation. In this group, 326 underwent PN and 53 received cryoablation.

"cryoablation and RFA have traditionally been thought to provide inferior results compared to surgical removal. Our findings of nearly equal success, if correct, should encourage further research on these treatment modalities in patients with kidney cancer in early stage, "says Dr. Thompson.