Seven physicians receive ASTRO grants to advance research in oncology radiation -
The American Society for Radiation Oncology (ASTRO) has selected seven major doctors to receive a total $ 675,000 in cash and prizes to advance research in oncology. The ASTRO Junior Faculty Price research training career, ASTRO Residents / Fellows in Radiation Oncology Research Seed Grant and / Radiation Oncology Institute ASTRO (ROI) Fellowship of the comparative effectiveness used to fund studies into the radiation and cancer biology, radiation physics, translational research findings / research on health services and comparative research of effectiveness in radiation oncology. Recipients will be recognized at the 56th Annual Meeting of ASTRO, September 14-17, 2014 at Moscone Center in San Francisco.
"the high-quality research is essential to the advancement of radiation oncology and provide the best possible treatment for our patients," said ASTRO President Colleen AF Lawton, MD, Fastro. "ASTRO is proud to support these seven outstanding researchers in their work to improve radiation oncology and treatment against cancer. "
the ASTRO Junior Faculty career research training Award provides $ 100,000 per year for two years to two winners ($ 0,000 to each recipient) to support the careers of promising junior faculty by providing the opportunity for time spent working on research projects in radiation oncology, biology, physics services or outcomes / health. recipients must be board eligible physicians, physicists in radiation oncology or radiation biologists during the first three years of their appointment of junior faculty
both winners ASTRO 2014 junior research training career faculty are :.
• Bryan Allen, MD, PhD, of the University of Iowa Hospitals and Clinics in Iowa City, Iowa. Dr. Allen is working to determine whether pharmacologic ascorbate can be used to modulate the sensitivity of chemoradiotherapy in non-small lung cancer and thus be used to improve outcomes in the treatment of lung cancer.
• Stephen Shiao, MD, PhD, of Cedars-Sinai Medical Center in Los Angeles. Dr. Shiao studying the mechanisms by which blocking the interleukin (IL) -4, a cytokine that controls the development of macrophages that suppress the immune response being, improves the response of the solid tumor to radiotherapy treatment.
The ASTRO Residents / Fellows in Radiation Oncology Research Seed Grant price of $ 25,000 for one-year projects for residents and fellows who intend to pursue careers focused on basic science or clinical research in radiation oncology services.
The three 2014 grant recipients are:
• Zachary Morris, MD, PhD, of the University of Wisconsin Hospitals and Clinics in Madison, Wisconsin. Dr. Morris compares the efficacy of the combinations of radiation, an antibody specific for the tumor that causes cytotoxicity dependent cell-mediated antibody and a checkpoint inhibitor with regard to the control of local sites, remote ( not radiated) and reintroduced disease to evaluate the immune response to these treatments. Previous research suggests radiation can compliment immunotherapies improving immune responsiveness of tumor cells.
• You Dan, MD, of Thomas Jefferson University in Philadelphia. Dr. Dan examines inhibition of miR-21, an oncogenic microRNAs to overcome treatment resistance and sensitize tumors to DNA damaging agents in the radioresistant breast cancer.
• Todd Aguilera, MD, PhD, Stanford Cancer Center in Stanford University, California. Dr. Aguilera is studying why tumor immunity often does not occur in a context of checkpoint blockade and evaluates the bystander effects of radiation which, when combined with radiation, can lead to immune responses in tumors untreated.
The ASTRO / ROI comparative effectiveness research Awar provides for $ 50,000 per year for two years to two researchers ($ 100,000 for each beneficiary) who will conduct comparative effectiveness research to examine the treatment of radiation oncology. Fellows are board-certified physicians or board eligible in radiation oncology when the price starts and focus on academic radiation oncology
The two 2014 recipients are :.
• Benjamin Smith, MD, of the University of Texas MD Anderson Cancer Center in Houston. Dr. Smith is working to enhance and personalize the selection of local therapy in elderly women with localized estrogen receptor positive breast cancer by comparing the quality of life outcomes for patients treated with four local therapy options: lumpectomy with whole breast irradiation, brachytherapy with lumpectomy, mastectomy and lumpectomy without radiation with endocrine therapy alone.
• James Murphy, MD, MS, of the University of California, San Diego. Dr Murphy examines hypofractionated radiation models of the breast, the study of the comparative effectiveness and evaluation of patient characteristics and suppliers associated with the use of hypofractionated against the standard fractionated radiotherapy.
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