Tuesday, August 27, 2013

Researchers develop device that sees lung cancer

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Researchers develop device that sees lung cancer -

Lung cancer causes more deaths in the United States that the three most common cancers combined (colon , breast and pancreas). The reason for the beating death rate is simple: poor detection. Lung cancer attacks without leaving fingerprints, quietly grieving victims and uncontrollable metastasized -. At the point of no return

Now, a new device developed by a team of researchers in the Israeli cancer, US and UK can reverse the trend by both lung cancer accurately detect and identify its phase progression. The breathalyzer test, embedded with a chip nanotech "NaNose" literally "smell" cancer tumors has been developed by Professor Nir Peled Sackler Faculty of Tel Aviv University of Medicine, Prof. Hossam Haick (inventor) of the Technion - Israel Institute of Technology and Professor Fred Hirsch of the University of Colorado School of Medicine in Denver.

The study, presented at a recent American Society of Clinical Oncology conference in Chicago, was conducted on 358 patients who were either diagnosed or at risk for lung cancer. Participants were enrolled at UC Denver, Tel Aviv University, the University of Liverpool, and Jacksonville, Florida, a center of influence. Other researchers included Dr. Paul Bunn UC Denver; Teacher. Douglas Johnson, Dr. Stuart Milestone, and Dr. John Wells in Jacksonville; Teacher. John Field from the University of Liverpool; and Dr. Maya Ilouze and Tali Feinberg TAU

The smell of cancer

"Lung cancer is a devastating disease, responsible for nearly 2,000 deaths Israel annually. - a third of all cancer deaths, "said Dr. Peled. "Lung cancer diagnostics require invasive procedures such as bronchoscopy, biopsy guided by computer, or surgery Our new device combines several new technologies with a new concept - .. Using the breath as cancer diagnosis means

"Our NaNose was able to detect lung cancer with 0 percent accuracy, even when the lung nodule was tiny and difficult to sample. He was even able to distinguish subtypes of cancer, which was unexpected, "said Dr. Peled.

The cancerous lung tumors produce chemicals called volatile organic compounds (VOCs), which evaporate easily into the air and produce a discernible flavor profile. Prof. Haick harnessed nanotechnology to develop very sensitive NaNose chip, which detects the unique 'signature' of VOCs in exhaled air. four out of five, the device differential between benign and malignant lung lesions and even different subtypes of cancer

the larger the tumor. -

"cancer cells not only have an odor or a different and unique signature, you can even discriminate between subtypes and the progress of the disease, "said Dr. Peled." over the tumor, the most robust of the signature. "

the device and subsequent sorted accurately analyzes the healthy people of people with lung cancer at an early stage 85 percent of the time, and healthy people to people advanced lung cancer 82 percent of the time. the test also distinguished accurately between early cancer and advanced lung 79 percent of the time.

"the device could be useful to help determine patients who need more intensive screening for lung cancer, "said Dr. Peled. "We hope to have a device that would be able to give you a go / Outcome-go - something wrong, go for an X-ray"

The Boston-based company Alpha Szenszor authorized. technology and hopes to bring to market in the coming years. Meanwhile, a new smaller version of the device has since been developed that can plug into the USB port of a computer.

the study was supported by the grant of the European Union LCAOS, a collaboration funded by the EU, which aims to enable the earliest possible detection of lung cancer, and the international Association for the study lung cancer (IASLC).


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