Wednesday, August 21, 2013

Phone weight loss-based intervention is effective in breast cancer treatment

Tags

Phone weight loss-based intervention is effective in breast cancer treatment -

A series of simple telephone call can make a big difference in helping women reach their treatment targets for breast cancer, according to a randomized trial of women who are obese, published online today in Journal of Clinical Oncology by Dr. Pamela Goodwin of Mount Sinai Hospital and Lunenfeld research Institute-Tanenbaum.

women received counseling on weight loss from a life coach trained by phone of a weight loss that was still evident after two years, reducing their risk of recurrence of cancer breast.

It is already known that women who are obese have about 25-30% greater risk of death compared to women who were not obese, said Dr. Goodwin. excess adipose tissue in the body stimulates inflammation, and is associated with alterations of hormones such as insulin, leptin and estradiol, which play a role in cancer growth and recurrence. "That's why breast cancer treatment for women who are overweight often include weight loss as an important treatment goal," she adds. Dr. Goodwin is director of the Centre Marvelle Koffler Mount Sinai, an investigator at theLunenfeld Tanenbaum-Research Institute of Mount Sinai Hospital and professor in the Department of Medicine of the University of Toronto.

Low -Cost response

"This study demonstrates a powerful result of lifestyle change which is notoriously difficult," says Dr. Goodwin. "As much as we we look to technology and the medical side of treatment, it is equally important to understand the power of low cost interventions can make a difference in the survival and quality of life of breast cancer, "she adds.

randomized trial of 338 women in Canada and the United States compared results in women who received counseling on weight loss from a life coach on the phone to the results in women who received a mailing. All participants in the study were postmenopausal and received an aromatase inhibitor (blocker estrogen). The results in terms of sustained weight loss after two years were comparable to those made by women who have had an in-person consultation on weight loss.

"In women who face the challenge of breast cancer compound and obesity, we can not ignore the importance of low cost support to which can contribute to improved survival "says Dr. Goodwin. large randomized trials are being planned to study the effects of weight loss intervention by telephone report on the results of breast cancer.

the document" a randomized trial of an intervention based on the weight loss phone in postmenopausal women with breast cancer receiving letrozole. the LISA trial "with the sponsors of Canada and Harvard Medical School Funders include Lunenfeld -Tanenbaum research Institute Foundation and Mount Sinai Hospital.


EmoticonEmoticon